Robb Read: Silicon Valley Takes On Death

Tech bigwigs are investing billions in pursuit of longer, disease-free lives.

By Megan Miller 29/04/2021

Entrepreneur Dave Asprey’s end-of-life plans are quite simple, really, even if some of his ambitions sound laughably optimistic to most of us. “I want to die at a time and by a method of my own choosing, and keep doing awesome things until that day,” he tells me. “I don’t think it’s outrageous to believe I’ll make it to 180 years old. And if I run out of energy, it’ll just be because I did too much cool shit for my own good.”

Asprey is strolling across his lush property in British Columbia, holding up his phone and pointing out the specimens in this year’s garden as we chat over
Zoom in the midst of the global pandemic. He’s protecting his skin from the sun with a goofy Outdoor Research hat and wearing a long string of beads that he says are each over a hundred years old, from cultures around the world.

Asprey, 48, is the founder of the Bulletproof wellness empire and a vocal champion of the movement to extend human life expectancy beyond 100 years. He’s made millions by experimenting on his own body and packaging his home-brewed discoveries into books, a podcast, consulting services and consumer products (you may have even tried his butter-laced coffee). Asprey, who was a web-security executive before he became the “Bulletproof Executive”, is just one of a cadre of tech elite who have begun directing their attention—and truckloads of money—toward the problem of life extension. Jeff Bezos, Peter Thiel, Sergey Brin, Larry Ellison—name a Silicon Valley A-lister and he or she is likely funding longevity research, experimenting with anti-ageing interventions or both. These masters of the universe see no reason why they can’t take the tech industry’s optimisation obsession and apply it to the ultimate challenge: conquering death itself.

And their efforts appear to be paying off. Thanks to a recent explosion of advances in longevity medicine, Asprey’s vision of living healthfully into his second century might not be so crazy. In fact, for people in middle age right now, a handful of therapies in clinical trials have the potential, for the first time in human history, to radically transform what “old age” looks like. If the life extensionists are right, a person who’s 40 today might reasonably expect to still be downhill skiing, running a 10K or playing singles tennis at 100.

“If you do anti-ageing right,” Asprey insists, “you’ll have a level of resilience and energy to fight what comes your way. If you get Covid-19, you’re less likely to become very sick. The idea is that at a cellular level, you’re making yourself very hard to kill.”

The most extreme of the controversial interventions Asprey has undergone involved having stem cells extracted from his own bone marrow and fat and then injected into hundreds of locations on his body. “Into every joint, between every vertebra and into my cerebrospinal fluid, face and sex organs,” he tells me cheerfully. “For what I spent on that, I could have bought a really nicely appointed Tesla.”

He trots up a flight of stairs to his home office, which sits above a million-dollar lab filled with health gadgets, such as a cryochamber, a hypoxic trainer and an AI-enabled stationary bike. “For a wealthy person, investing in your body should be a major part of your ‘I’m rich’ strategy,” he explains. “Personally, I think you should be spending at least 2 to 3 percent of your net worth on health and longevity. Get a personal chef who can cook you the right food. It’s not that hard.”

It might be an exaggeration to say BioViva CEO Liz Parrish believes death is optional, but for her, Asprey’s goal of living to 180 shows a distinct lack of ambition. “If you can reach homeostasis in the body,” Parrish says, “where it’s regenerating itself just a little bit faster than it’s degrading, then what do you die of? An accident or natural disaster, probably. There’s no expiration date at 90 or 100 years old.”

Tall, blonde and fit, Parrish cuts a strikingly youthful figure at 49—one that might convince you to order whatever she’s having. But, like Asprey, she has received criticism from the longevity research community for becoming “patient zero” in her own experimental drug trial, aimed at halting ageing at the cellular level. In 2015, Parrish underwent telomerase and follistatin gene therapies in Bogotá, Colombia. The procedures involved receiving around a hundred injections of a cocktail of genes and a virus modified to deliver those new genes into her body’s cells. The objective was to prevent age-related muscle loss and lengthen her telomeres: the “caps” at the end of our chromosomes. Scientists have identified their unravelling as not only a markerof ageing but also a potential cause of age-related decline.

Parrish told the media about her clandestine experiment and has published periodic updates on her condition in the five years since, and she reports that she has indeed increased her muscle mass and lengthened her telomeres. Parrish’s punk-rock approach stems from her conviction that the medical research community— both the Food and Drug Administration (FDA) and researchers who aren’t business-minded—is moving too slowly, with too much red tape, when it comes to advancing ageing therapeutics. But gene therapy is a relatively new area of medicine that brings with it a host of new risks, including cancer, severe immune reactions and infections caused by the viral vector used to deliver the drug.

Parrish downplays such worries. “There may be risks with this,” she tells Robb Report. “But the known risk is that you’re 100 per cent likely to die. So you
have to decide for yourself if the potential benefit outweighs that.”

Humans have always aspired to find the fountain of youth, so people might be sceptical about the fact that anti-ageing technologies are working now,” says British investor and businessman Jim Mellon. “But the fact is that this is finally happening, and we need to seize the moment.” Mellon cofounded Juvenescence, a three-year-old pharmaceutical company that’s investing in multiple technologies simultaneously to increase the odds of bringing winning products to market.

Mellon, 63, has made his fortune betting on well-timed investment opportunities, and he predicts that a new “stock-market mania” for life extension is just around the corner. “This is like the internet dial-up phase of longevity biotech,” he enthuses. “If you’d invested in the internet in the

Below, some industry-leaders on their life elongating routines.

Liz Parrish

CEO, BioViva

Sleep routine

Wake naturally.

Vitamin/supplements

Vitamin B12 and occasional multivitamin and mineral.

Diet

Vegetarian.

Mindfulness practice

Nightly meditation.

Exercise regimen

30 minutes of cardio and 10 minutes of weights, five days a week.

Anti-ageing solution

“Regenerative gene therapies. I’m certain most people will take them in the next couple of decades.”

180th-birthday wish

“Solving another critical issue.”

Dave Asprey

Founder, Bulletproof

Vitamins/supplements/

prescription meds

“A carefully crafted stack of 150 capsules a day,” including resveratrol, KetoPrime, Brain Octane and rapamycin.

Diet

Bulletproof Diet, including intermittent fasting with Bulletproof Coffee; fast 24 to 56 hours once every month or two.

Mindfulness exercises

“A short gratitude practice, and some light breathing and tai chi” each morning; 40 Years of Zen, a five-day program, once or twice a year.

Exercise regimen

90 minutes a week on AI bike and electrical stimulation on muscles. “I spend as little time as humanly possible on exercise, as long as I get the results I want.”

Anti-ageing solution

“Sleeping with a bite guard to protect your molars from wearing down over time. It changes your brain in a bad way when that happens!”

180th-birthday wish

“Either a cruise to Mars or a 1970 Mustang Fastback, which by then will be 210 years old!”

Eric Verdin

President and CEO,

Buck Institute

Sleep Routine

Avoid: coffee after 2 p.m., heavy workouts after 6 p.m., alcohol during the week and heavy eating in the evening.

Vitamins/supplements

Vitamin D, omega fatty acids, NMN, citrus bioflavonoids complex, fibre supplement, prebiotic supplement.

Diet

Fasting-mimicking diet once every four to six months; roughly 16:8 intermittent fasting at other times.

Mindfulness practice

Daily meditation.

Anti-ageing solution

“I love cooking and eating, so I do not restrict food on the weekend. Happiness with friends and family is the surest path to longevity.”

100th-birthday wish

“A bike tour across the US, from coast to coast.”

Jim Mellon

Cofounder, Juvenescence

Sleep routine

7.5 hours plus a 30-minute nap; in bed by 9pm

Vitamins/supplements/Prescription meds

Vitamins D and B12, metformin.

Exercise regimen

Walk or run a minimum 10,000 steps a day; weights three times a week.

Anti-ageing solution

Green tea.

100th-birthday wish

“Another 25 years.”

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8 Fascinating Facts You Didn’t Know About Aston Martin

The British sports car company is most famous as the vehicle of choice for James Bond, but Aston Martin has an interesting history beyond 007.

By Bob Sorokanich 01/05/2024

Aston Martin will forever be associated with James Bond, ever since everyone’s favourite spy took delivery of his signature silver DB5 in the 1964 film Goldfinger. But there’s a lot more to the history of this famed British sports car brand beyond its association with the fictional British Secret Service agent.

Let’s dive into the long and colourful history of Aston Martin.

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What Venice’s New Tourist Tax Means for Your Next Trip

The Italian city will now charge visitors an entry fee during peak season. 

By Abby Montanez 01/05/2024

Visiting the Floating City just got a bit more expensive.

Venice is officially the first metropolis in the world to start implementing a day-trip fee in an effort to help the Italian hot spot combat overtourism during peak season, The Associated Press reported. The new program, which went into effect, requires travellers to cough up roughly €5 (about $AUD8.50) per person before they can explore the city’s canals and historic sites. Back in January, Venice also announced that starting in June, it would cap the size of tourist groups to 25 people and prohibit loudspeakers in the city centre and the islands of Murano, Burano, and Torcello.

“We need to find a new balance between the tourists and residents,’ Simone Venturini, the city’s top tourism official, told AP News. “We need to safeguard the spaces of the residents, of course, and we need to discourage the arrival of day-trippers on some particular days.”

During this trial phase, the fee only applies to the 29 days deemed the busiest—between April 25 and July 14—and tickets will remain valid from 8:30 am to 4 pm. Visitors under 14 years of age will be allowed in free of charge in addition to guests with hotel reservations. However, the latter must apply online beforehand to request an exemption. Day-trippers can also pre-pay for tickets online via the city’s official tourism site or snap them up in person at the Santa Lucia train station.

“With courage and great humility, we are introducing this system because we want to give a future to Venice and leave this heritage of humanity to future generations,” Venice Mayor Luigi Brugnaro said in a statement on X (formerly known as Twitter) regarding the city’s much-talked-about entry fee.

Despite the mayor’s backing, it’s apparent that residents weren’t totally pleased with the program. The regulation led to protests and riots outside of the train station, The Independent reported. “We are against this measure because it will do nothing to stop overtourism,” resident Cristina Romieri told the outlet. “Moreover, it is such a complex regulation with so many exceptions that it will also be difficult to enforce it.”

While Venice is the first city to carry out the new day-tripper fee, several other European locales have introduced or raised tourist taxes to fend off large crowds and boost the local economy. Most recently, Barcelona increased its city-wide tourist tax. Similarly, you’ll have to pay an extra “climate crisis resilience” tax if you plan on visiting Greece that will fund the country’s disaster recovery projects.

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Omega Reveals a New Speedmaster Ahead of the Paris 2024 Olympics

Your first look at the new Speedmaster Chronoscope, designed in the colour theme of the Paris Olympics.

By Josh Bozin 26/04/2024

The starters are on the blocks, and with less than 100 days to go until the Paris 2024 Olympics, luxury Swiss watchmaker Omega was bound to release something spectacular to mark its bragging rights as the official timekeeper for the Summer Games. Enter the new 43mm Speedmaster Chronoscope, available in new colourways—gold, black, and white—in line with the colour theme of the Olympic Games in Paris this July.

So, what do we get in this nicely-wrapped, Olympics-inspired package? Technically, there are four new podium-worthy iterations of the iconic Speedmaster.

Omega

The new versions present handsomely in stainless steel or 18K Moonshine Gold—the brand’s proprietary yellow gold known for its enduring shine. The steel version has an anodised aluminium bezel and a stainless steel bracelet or vintage-inspired perforated leather strap. The Moonshine Gold iteration boasts a ceramic bezel; it will most likely appease Speedy collectors, particularly those with an affinity for Omega’s long-standing role as stewards of the Olympic Games.

Notably, each watch bears an attractive white opaline dial; the background to three dark grey timing scales in a 1940s “snail” design. Of course, this Speedmaster Chronoscope is special in its own right. For the most part, the overall look of the Speedmaster has remained true to its 1957 origins. This Speedmaster, however, adopts Omega’s Chronoscope design from 2021, including the storied tachymeter scale, along with a telemeter, and pulsometer scale—essentially, three different measurements on the wrist.

While the technical nature of this timepiece won’t interest some, others will revel in its theatrics. Turn over each timepiece, and instead of a transparent crystal caseback, there is a stamped medallion featuring a mirror-polished Paris 2024 logo, along with “Paris 2024” and the Olympic Rings—a subtle nod to this year’s games.

Powering this Olympiad offering—and ensuring the greatest level of accuracy—is the Co-Axial Master Chronometer Calibre 9908 and 9909, certified by METAS.

Omega

A Speedmaster to commemorate the Olympic Games was as sure a bet as Mondo Deplantis winning gold in the men’s pole vault—especially after Omega revealed its Olympic-edition Seamaster Diver 300m “Paris 2024” last year—but they delivered a great addition to the legacy collection, without gimmickry.

However, the all-gold Speedmaster is 85K at the top end of the scale, which is a lot of money for a watch of this stature. By comparison, the immaculate Speedmaster Moonshine gold with a sun-brushed green PVD “step” dial is 15K cheaper, albeit without the Chronoscope complications.

The Omega Speedmaster Chronoscope in stainless steel with a leather strap is priced at $15,725; stainless steel with steel bracelet at $16,275; 18k Moonshine Gold on leather strap $54,325; and 18k Moonshine Gold with matching gold bracelet $85,350, available at Omega boutiques now.

Discover the collection here

 

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Here’s What Goes Into Making Jay-Z’s $1,800 Champagne

We put Armand de Brignac Blanc de Noirs Assemblage No. 4 under the microsope.

By Mike Desimone And Jeff Jenssen 23/04/2024

In our quest to locate the most exclusive and exciting wines for our readers, we usually ask the question, “How many bottles of this were made?” Often, we get a general response based on an annual average, although many Champagne houses simply respond, “We do not wish to communicate our quantities.” As far as we’re concerned, that’s pretty much like pleading the Fifth on the witness stand; yes, you’re not incriminating yourself, but anyone paying attention knows you’re probably guilty of something. In the case of some Champagne houses, that something is making a whole lot of bottles—millions of them—while creating an illusion of rarity.

We received the exact opposite reply regarding Armand de Brignac Blanc de Noirs Assemblage No. 4. Yasmin Allen, the company’s president and CEO, told us only 7,328 bottles would be released of this Pinot Noir offering. It’s good to know that with a sticker price of around $1,800, it’s highly limited, but it still makes one wonder what’s so exceptional about it.

Known by its nickname, Ace of Spades, for its distinctive and decorative metallic packaging, Armand de Brignac is owned by Louis Vuitton Moët Hennessy and Jay-Z and is produced by Champagne Cattier. Each bottle of Assemblage No. 4 is numbered; a small plate on the back reads “Assemblage Four, [X,XXX]/7,328, Disgorged: 20 April, 2023.” Prior to disgorgement, it spent seven years in the bottle on lees after primary fermentation mostly in stainless steel with a small amount in concrete. That’s the longest of the house’s Champagnes spent on the lees, but Allen says the winemaking team tasted along the way and would have disgorged earlier than planned if they’d felt the time was right.

Chef de cave, Alexandre Cattier, says the wine is sourced from some of the best Premier and Grand Cru Pinot Noir–producing villages in the Champagne region, including Chigny-les-Roses, Verzenay, Rilly-la-Montagne, Verzy, Ludes, Mailly-Champagne, and Ville-sur-Arce in the Aube département. This is considered a multi-vintage expression, using wine from a consecutive trio of vintages—2013, 2014, and 2015—to create an “intense and rich” blend. Seventy percent of the offering is from 2015 (hailed as one of the finest vintages in recent memory), with 15 percent each from the other two years.

This precisely crafted Champagne uses only the tête de cuvée juice, a highly selective extraction process. As Allen points out, “the winemakers solely take the first and freshest portion of the gentle cuvée grape press,” which assures that the finished wine will be the highest quality.  Armand de Brignac used grapes from various sites and three different vintages so the final product would reflect the house signature style. This is the fourth release in a series that began with Assemblage No. 1. “Testing different levels of intensity of aromas with the balance of red and dark fruits has been a guiding principle between the Blanc de Noirs that followed,” Allen explains.

The CEO recommends allowing the Assemblage No. 4 to linger in your glass for a while, telling us, “Your palette will go on a journey, evolving from one incredible aroma to the next as the wine warms in your glass where it will open up to an extraordinary length.” We found it to have a gorgeous bouquet of raspberry and Mission fig with hints of river rock; as it opened, notes of toasted almond and just-baked brioche became noticeable. With striking acidity and a vein of minerality, it has luscious nectarine, passion fruit, candied orange peel, and red plum flavors with touches of beeswax and a whiff of baking spices on the enduring finish. We enjoyed our bottle with a roast chicken rubbed with butter and herbes de Provence and savored the final, extremely rare sip with a bit of Stilton. Unfortunately, the pairing possibilities are not infinite with this release; there are only 7,327 more ways to enjoy yours.

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Bill Henson Show Opens at Roslyn Oxley9 Gallery

Dark, grainy and full of shadows Bill Henson’s latest show draws on 35 mm colour film shot in New York City in 1989.

By Belinda Aucott-christie 20/04/2024

Bill Henson is one of Australia’s best-known contemporary photographers. When a show by this calibre of artist opens here, the art world waits with bated breath to see what he will unveil.

This time, he presents a historically important landscape series that chronicles a time in New York City that no longer exists. It’s a nostalgic trip back in time, a nocturnal odyssey through the frenetic, neon-lit streets of a long-lost America.

Known for his chiaroscuro style, Henson’s cinematic photographs often transform his subject into ambiguous objects of beauty. This time round, the show presents a mysterious walk through the streets of Manhattan, evoking a seedy, yet beautiful vision of the city. 

Bill Henson Untitled, 1989. Archival inkjet pigment print 127 x 180 cm Edition of 5 + 2AP Courtesy of Roslyn Oxley Gallery
Installation shot of Bill Henson’s show,’The Liquid Night’ at Roslyn Oxley9 Gallery.

Relying on generative gaps, these landscapes result from Henson mining his archive of negatives and manipulating them to produce a finished print. Sometimes, they are composed by a principle of magnification, with Henson honing in on details, and sometimes, they are created through areas of black being expanded to make the scene more cinematic and foreboding. Like silence in a film or the pause in a pulse, the black suggests the things you can’t see. 

Bill Henson, Untitled, 1989 Archival inkjet pigment print 127 x 180 cm Edition of 5 + 2AP Courtesy of Roslyn Oxley9 Gallery
Bill Henson, Untitled, 1989 Archival inkjet pigment print 127 x 180 cm Edition of 5 + 2AP Courtesy of Roslyn Oxley9 Gallery
Bill Henson Untitled, 1989 Archival inkjet pigment print 127 x 180 cm Edition of 5 + 2AP Courtesy of Roslyn Oxley9 Gallery

Henson’s illustrious career has spanned four decades and was memorably marred by controversy over a series of nude adolescent photographs shown in 2008, which made him front-page news for weeks. This series of portraits made Henson the subject of a police investigation during which no offence was found. 

In recent years, Henson has been a sharp critic of cancel culture, encouraging artists to contribute something that will have lasting value and add to the conversation, rather than tearing down the past.

Untitled 2/1, 1990-91 from the series Paris Opera Project type C photograph 127 x 127 cm; series of 50 Edition of 10 + AP 2

His work deals with the liminal space between the mystical and the real, the seen and unseen, the boundary between youth and adulthood.

His famous Paris Opera Project, 1990-91, pictured above, is similarly intense as the current show, dwelling on the border between the painterly and the cinematic.

Bill Henson’s ‘The Liquid Night’ runs until 11 May 2024 at Roslyn Oxley9 Gallery.

Roslyn Oxley9 Gallery, 8 Soudan Ln, Paddington NSW; roslynoxley9.com.au 

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